The classical features of IRIDA patients are: increased plasma hepcidin levels,18 moderate/severe anemia (Hemoglobin (Hb) 6–9 g/dl), hypochromic, microcytic anemia (MCV 45–65 fL), low transferrin saturation (<5%), normal or even moderately elevated serum ferritin level, normal C‐reactive protein.19, 20, 21. Here, TF is linked to anemia (phenotype).