We found that there was a significant (P<0.05) differential expression (≥ 1.4 or ≤ -1.4-fold, RPKM ≥ 0.5) of 8 genes in the ear tumors, of which one (Cln8) had a viral DNA integrated in a 6-kb terminal exon and was upregulated. This evidence concerns the gene CLN8 and ear neoplasm.