LCN2 expression is higher in solid tumors than in corresponding normal tissues [25, 41], and it is mainly described as tumor promoter in many cancers, including pancreas, glioblastoma, thyroid, kidney, esophagus, and breast cancer [19, 28, 42, 43, 44, 45, 46, 47, 48]. This evidence concerns the gene LCN2 and glioblastoma.