On histologic examination, tumors generated from LCN2‐silenced cells were more differentiated than those generated from control SUM149 cells (Fig. 4E); we further observed tumor emboli, another hallmark of IBC tumors, in SUM149 control‐transplanted tumors but not in tumors generated from LCN2‐silenced SUM149 cells (Fig. 4E). The gene discussed is LCN2; the disease is neoplasm.