Silencing of LCN2 reduced tumor volumes (P = 0.0037; Fig. 4A) and tumor latency, that is, the ability to initiate tumor growth: mice transplanted with SUM149 LCN2‐silenced cells took longer to initiate tumors than did those transplanted with SUM149 control cells (P = 0.0145; Fig. 4B). Here, LCN2 is linked to neoplasm.