In contrast to AUC-GLP-1, fasting GLP-1 level ≤ 1 pmol/l, a level below or at lower limit of assay sensitivity, was not selected as an explanatory variable for Gensini score ≥ 10 in multivariate logistic analysis in which sex, age, BMI, HOMA-IR, history of hypertension, LDL-cholesterol, HDL-cholesterol and eGFR were used as other possible variables (Supplementary Table 2). The gene discussed is GCG; the disease is hypertensive disorder.