PKD2 and autosomal dominant polycystic kidney disease: ADPLD has been linked to mutations in PRKCSH and SEC63, while the causative mutation of PLD that is associated with ADPKD is PKD1 or PKD2. There is no difference in the PKD1 and PKD2 mutation prevalence between ethnicities, but the PRKCH gene mutation has been reported in Holland, Belgium, Finland, and North America, but not in Taiwan [4, 5].