Among the BCP-ALL ‘other’ cases, CRLF2 showed a clear bimodal expression (Additional file 2: Fig. S2B), with a significant higher CRLF2 expression in the BCR-ABL1-like group, as compared to the non BCR-ABL1-like cases (logFC 5.17, P < 0.0001). This evidence concerns the gene CRLF2 and acute lymphoblastic leukemia.