We observed an age-dependent increase in Iba1 load in the schizophrenia cases with psychosis at death which was not observed in schizophrenia without psychosis and controls (interaction between group (3 levels) and age: F = 3.66, p = 0.031 in grey matter; F = 3.03, p = 0.055 in white matter; Dunnett’s test for multiple comparisons Sz+ vs. The gene discussed is AIF1; the disease is psychotic disorder.