HLA-C and schizophrenia: Increased risk for schizophrenia is conferred by interplay of early environmental exposure to proinflammatory immune responses and risk alleles in immune genes (Brown et al., 2004, Corvin and Morris, 2014, Ellman et al., 2010, Purcell et al., 2009), the strongest of which is in the major histocompatibility complex (MHC) locus on chromosome 6 (Purcell et al., 2009), encoding human leukocyte antigen (HLA) (Schizophrenia Working Group of the Psychiatric Genomics, 2014).