CRBN and infection: Adding dTag1 degrader to HCMV UL87HF-infected HFF for 6 h in late infection depleted the UL87 LTF [24] via the host proteasome after dTag1 joins the FKBP12F36V segment of the chimeric UL87 LTF to the host cereblon E3 ligase complex (Fig 1B).