TNF and infection: We found that T. marneffei infection induced CD163 and CD200R expression in human monocytes/macrophages at 12 h and 24 h post-infection (Figure 3a, b), the same as TNF-α and IL-10 up-regulation at 24 h post-infection (Figure 3c, d), suggesting that T. marneffei infection also enhanced polarization toward the M2-like phenotype in human monocytes/macrophages.