Furthermore, a T cell-restricted Srsf1-deficient mice develops systemic autoimmunity and lupus-nephritis (Katsuyama et al., 2019; Paz et al., 2021), whereas Srsf1 deletion in myogenic progenitors leads to defects in neuromuscular junctions (Liu et al., 2020). The gene discussed is SRSF1; the disease is lupus nephritis.