Because we found that our chronic DUX4-expressing mouse model also develops late-onset, accumulative FSHD-like pathology including immune infiltration, we further investigated the immune/regeneration-related miRNA profile in the later phases of pathogenesis after 1.5 years of exposure to chronic DUX4 expression in skeletal muscle. Here, DUX4 is linked to facioscapulohumeral muscular dystrophy.