For example, O‐GlcNAcylation of PGK1 at threonine 255 regulates the glycolysis and promotes the development of colon cancer,36 acetylation of PGK1 at K323 contributes to liver progression,13 phosphorylation of PGK1 at Y324 devote to glioblastoma multiforme formation.37 This evidence concerns the gene PGK1 and glioblastoma.