PTEN and myocardial infarction: Overexpression miR-19a/19b by intra-cardiac injection of miRNA mimics is capable to stimulate cardiomyocytes proliferation and repairs the adult heart after myocardial Infarction with downregulated PTEN expression level (Gao et al. 2019), whereas overexpression of PTEN reverses miR-19-induced proliferation in cultured cardiomyocytes (Chen et al. 2013).