Prostate cancer noncoding RNA 1 (PRNCR1), an lncRNA transcribed from 8q24, by activating the androgen receptor (AR), contributes in the carcinogenesis of prostate cancer, and polymorphisms in the lncRNA PRNCR1 are a risk for different cancers such as prostate cancer, colorectal cancer, and gastric cancer (8). The gene discussed is PRNCR1; the disease is colorectal cancer.