Considering that transcription factor LEF1 is reported to be involved in lung cancer metastasis [20], and there is a steric hindrance effect that the binding of lncRNA OXCT1-AS1 to the 55 position of LEF1 affects the ubiquitination of LEF1 at the 54 position, we selected LEF1 as a target. The gene discussed is OXCT1; the disease is lung cancer.