LGALS3 and hydrops fetalis: HF is a complex syndrome involving different pathophysiological pathways (e.g., remodeling, myocardial injury, fibrosis, and inflammation), the components of which can be reflected by various biomarkers, including natriuretic peptides, PAB, galectin-3, soluble suppressor of tumorgenicity 2 (ST-2), Cys-C, interleukin-6 (IL-6), highly sensitive troponin, and procalcitonin (21, 29).