Limitations of this study include not examining S-nitrosylation of Myo9A and its interacting partners in biopsy samples from DKD patients, in proximal tubular cells, glomerular endothelial and mesangial cells, known to be involved in DKD progression, nor in additional experimental T1D and T2D models. The gene discussed is MYO9A; the disease is type 1 diabetes mellitus.