The association of HLA-A*02:06 and HLA-B*44:03 was found to be associated with cold medicine-induced SJS/TEN in Japanese (55), and the same susceptible genes were verified in patients of other populations, such as HLA-B*44:03 in Indian and Brazilian, and HLA*02:06 in Korean (56). This evidence concerns the gene HLA-A and toxic epidermal necrolysis.