RUNX1 and precursor B-cell acute lymphoblastic leukemia: Due to the low incidence of the B-ALL disease, the overall survival of Sca1-ETV6-RUNX1 + Kdm5cf/wt + Sca1-Cre was not significantly reduced compared to WT mice [p-value = 0.1695; log-rank (Mantel–Cox) test Figure 5C].