After adjusting the correlations by purity, we found that MUC4 expression has a positive correlation with NOS2 (M1) (R = 0.201, p = 1.39e-05) and MRC1 (M2) (R = 0.127, p = 6.18e-03) but negative relevance to CD19 (B cell) (R = −0.117, p = 1.17e-02), CD86 (tumor-associated macrophages, TAM) (R = −0.132, p = 4.41e-03), ROS1 (M1) (R = −0.121, p = 9.2e-03), and CD14 (monocyte) (R = −0.188, p = 5.04e-05) in KIRC. The gene discussed is CD86; the disease is neoplasm.