PTPRN2 and diabetes mellitus: Importantly, we found that some DMRs were involved in biological pathways that were important for development and metabolism, such as embryonic skeletal system development and diabetes mellitus, indicating that specific genes, namely, HOXA3, bone morphogenetic protein 4 (BMP4), PTPRN2 and interleukin 1 beta (IL1B), which were influenced by DNA methylation.