H&E staining of tumor sections showed that abnormal mitoses in mammary tumor tissue of JFKTG/PyMTTG mice are about 3-fold greater in number than in JFKWT/PyMTTG mice (Figure 1E), clearly suggesting that JFK overexpression somehow promotes cell division of breast cancer cells in vivo. The gene discussed is FBXO42; the disease is breast carcinoma.