Confirming previous reports, we found mutual exclusive mutations between IDH1 and IDH2 (Yan et al., 2009), between IDH2 and TET2 (Gaidzik et al., 2012), between TET2 and WT1 (Wang et al., 2015), and between IDH1-EGFR (Agnihotri et al., 2014) in AML and LGG (Figures 1D,E). The gene discussed is IDH2; the disease is acute myeloid leukemia.