EBV-encoded miRNA BART12 could promote cell migration and invasion of EBV-associated NPC and gastric cancer by inhibiting TPPP1 mRNA and activating the cellular EMT process (Wu et al., 2020), and miR-BART15-5p could target BRUCE mRNA and TAX1BP1 gene in cancer cells and increase apoptosis and chemosensitivity to 5-FU (Choi et al., 2013; Choi and Lee, 2017). This evidence concerns the gene TPPP and nasopharyngeal carcinoma.