As expected, the serum level of MPO-DNA complexes was significantly increased in ARDS patients compared with healthy controls and sepsis patients [1.3 (0.6-1.7) vs. 0.6 (0.2-0.9), P<0.001, 1.3 (0.6-1.7) vs. 1.0 (0.7-1.2), P=0.011, respectively, Figure 1D]. The gene discussed is MPO; the disease is acute respiratory distress syndrome.