Meanwhile, in human endometrioid endometrial adenocarcinoma, hsa-miR-193a-5p act directly on YY1 to inhibit its transcription and translation, thereby inhibiting the proliferation and migration of cancer cells (17).So far, there have been no reports on whether lnc-TLCD2-1 can interact with hsa-miR-193a-5p in CRC to regulate YY1/NF-кB-p65 and affect the sensitivity of CRC to radiotherapy. The gene discussed is YY1; the disease is colorectal carcinoma.