AKT1 and Chagas disease: As for enrichment in the KEGG pathway, mainly in the following: HTLV-I infection, Jak-STAT signaling pathway, regulation of actin cytoskeleton, sphingolipid signaling pathway, hematopoietic cell lineage, inflammatory mediator regulation of TRP channels, chagas disease (American trypanosomiasis), leukocyte transendothelial migration, PI3K-Akt signaling pathway (Figure 8D).