Moreover, activated leukocyte cell adhesion molecule (ALCAM), the tubulin-detyrosinating activity of VASH1, lysophosphatidylcholine acyltransferase 1 (LPCAT1), and the TAZ-AXL-ABL2 feed-forward signaling axis are also essential for the formation of brain metastases from NSCLC (17–20). The gene discussed is LPCAT1; the disease is non-small cell lung carcinoma.