In contrast, we noted that the SNV or INDEL mutations were commonly detected in MYC, TP53, USH2A, NOTCH1 and PIK3CA genes in breast cancer samples (Supplementary Table 8), while MTOR, KMT2C, EGFR, USH2A and NF1 amplification were frequently found in breast cancer samples (Figure 3 and Supplementary Table 9). The gene discussed is TP53; the disease is breast cancer.