These risk exosomal microRNAs, as well as the corresponding interaction network or enrichments based on their targets (such as TAOK1, CMTM6, SCN3A, WASF3, IGF1, CNOT7, GABRG1, PRKD1) may provide a better understanding of the molecular mechanisms in the GC development. This evidence concerns the gene IGF1 and gastric cancer.