Moreover, GSEA querying of the hallmark gene sets using the array-based transcriptomic profiles from 7 additional independent cohorts of HNSCC patients obtained from either NCBI GEO (GSE10300, GSE27020, GSE30784, GSE41613, GSE65858) or ArrayExpress databases (E-TABM-302), confirmed a positive correlation between DCLK1 expression and the NOTCH pathway in all 7 publicly available data sets analyzed (Figure 4E). The gene discussed is DCLK1; the disease is head and neck squamous cell carcinoma.