SERPINA2 and esophageal squamous cell carcinoma: Expression of 42 ARGs was found to more effectively discriminate ESCC from normal esophagus with AUC ≥ 0.85, q < 0.0001, |log2(FC)| ≥ 0.5 (Supplementary Table 2), including 17 upregulated ARGs (Figure 1B) and 25 downregulated ARGs (Figure 1C).