IDH1 and central nervous system cancer: To verify that previous identified prognostic genes of TCGA-glioma PTEN-mut are also the prognostic genes in IDH1-wt patients with PTEN-mut, we observed that AEBP1, CLCF1, and OS9 were significantly prognostic genes in IDH1-wt, IDH1-wt/GBM, or IDH-wt/LGG gliomas with PTEN-mut (Figures 5C–F).