A CD4+ T‐cell response with CDI ≥ 3.0 to any epitope was detected in 91% (29/32) of participants with T1D ≤ 3 months, 82% (14/17) of AB‐positive FDR, 78% (7/9) of AB‐negative FDR, 35% (14/40) of T1D onset > 3 months and 31.35% (5/16) of healthy controls (Table 2). This evidence concerns the gene CD4 and clostridium difficile infection.