The cytokine profile delivered by immune cells decides the response of the immune system: TH1 cytokines (e.g., IL-2, IFN-γ, and tumour necrosis factor α (TNFα)) favour cell-mediated immunity; TH2 cytokines (e.g., IL-4, 5, 10, and 13) are significant for humoral immunity and allergy; and TH17 cytokines (e.g., IL-17, 22, and granulocyte-colony stimulating factor (G-CSF)) lead to an inflammatory response. The gene discussed is CSF3; the disease is allergic disease.