Macrophages linked to cancer such as monocytes, NK cells, MCs, and innate immune system preserve carcinogenesis as the tumour necrosis factor (TNF) and proinflammatory ME mediated by interleukins (ILs), for EMT to take place, stimulate the Nuclear Factor- (NF-) κB, helping other transcriptional factors [47]. This evidence concerns the gene TNF and cancer.