As shown in Figure 3, the absorbance value of the asthma + LY294002 group was lower than that of the asthma group (p < 0.05) and the absorbance value of the asthma + diazoxide + LY294002 group was also lower than that of the asthma + diazoxide group (p < 0.05), indicating that LY294002 (a PI3K/AKT pathway inhibitor) reversed the effects of diazoxide on the proliferative ability of ASMCs in the rat model of asthma. The gene discussed is AKT1; the disease is asthma.