CD274 and hepatocellular carcinoma: Based on this evidence, in a larger cohort of 87 patients with various stages of HCC (49 early‐stage, 22 locally advanced, and 16 metastatic), PD-L1+ CTCs were identified in 4 of 49 early‐stage patients, 12 of 22 (54.5%) locally advanced and 15 of 16 (93.8%) metastatic patients.