Furthermore, Raimondi et al.142 demonstrated that PD-L1-positive CTCs isolated from NSCLC patients were characterized by partial epithelial-mesenchymal transition phenotype and hypothesized that co-expression of PD-L1 and epithelial-mesenchymal transition cellular markers might represent a possible molecular background for the immune escape. This evidence concerns the gene CD274 and non-small cell lung carcinoma.