SNAI1 and carcinoma: Moreover, when we compared carcinomas from both mice groups, obtained at later times in PyMT-VE-CadhSnail1KO than in PyMT-VE-CadhSnail1CT mice, we observed that the carcinoma morphology was not the same in both models: whereas in control animals were mostly solid, invasive and poorly differentiated carcinomas, in endothelial Snail1-depleted mice, they were papillary, non-invasive and more differentiated carcinomas.