Moreover, we observed that degradation rate of ELAVL1 was markedly attenuated in PCa cells in response to METTL3 knockdown (Figure 5B-C and Figure S7B-C), while no significant changes of synthesis rate of ELAVL1 was observed (Figure 5D-E and Figure S7D-E). The gene discussed is METTL3; the disease is posterior cortical atrophy.