In a study published in 2017, a cohort of 116 HCC patients with survival data and corresponding circRNA-MTO1 expression were collectively analyzed by Kaplan-Meier survival curve, revealing the positive correlation between circRNA-MTO1 expression and prognosis of HCC patients and thus suggesting its potential as a prognosis biomarker 91. Here, MTO1 is linked to hepatocellular carcinoma.