Venn diagram showed that ten genes CCDC109B, CD58, CDHR1, CLIC1, EFEMP2, EMP3, LAMC1, LGALS1, PDLIM1 and TNFRSF1A were commonly differentially expressed between GBM and LGG subtypes in TCGA, CGGA, GSE4412 and GSE43378 datasets (Fig. 1C). Here, EMP3 is linked to glioblastoma.