The five most frequent genes were GJB2 (33 patients), SLC26A4 (16 patients), MYO15A (5 patients), OTOF (5 patients), and CDH23 (5 patients), while only four deafness genes were identified by 159 variant testing, and the frequency of these four genes was 45 (GJB2), 27 (SLC26A4), 2 (GJB3), and 1 (MT-RNR1), respectively. This evidence concerns the gene MCAT and deafness.