CD4 and neoplasm: CIBERSORT analysis showed that NPM1 expression level had correlation with tumor immune cell infiltration (Figure 5C), including B cell memory (P < 0.001), B cell plasma (P = 0.003), T cell CD4+ memory activated (P = 0.004), T cell regulatory (Tregs) (P < 0.001), T cell gamma delta (P = 0.031), NK cell activated (P = 0.036), Macrophage M0 (P < 0.001), Macrophage M2 (P = 0.007), Myeloid dendritic cell resting (P = 0.032) and Myeloid dendritic cell activated (P < 0.001).