KMT2D and lymphoma: Integrative genomic analyses from human samples carrying KMT2D mutations and Kmt2d-mouse FLs showed that genes differentially expressed in Kmt2d-mutated lymphomas were mostly repressed and affected a set of genes involved in terminal differentiation programs and GC exit, such as CD40 and BCR signaling, regulation of apoptosis, control of cell migration and proliferation.