However, the immune-associated genes in SLE were mainly associated with cytokines, including IL1B, TNF, CXCL8, CCL20, CCL4, CXCL1, CXCL2, CXCL3, CXCR1, CXCR2 and so on. The gene discussed is CXCR1; the disease is systemic lupus erythematosus.