However, the immune-associated genes in SLE were mainly associated with cytokines, including IL1B, TNF, CXCL8, CCL20, CCL4, CXCL1, CXCL2, CXCL3, CXCR1, CXCR2 and so on. Here, CXCL8 is linked to systemic lupus erythematosus.