PPARG and plasma cell myeloma: After this, Emma Morris discussed the effects of PPARγ agonist BAGDE on myeloma cells and bone marrow adipocytes (28), Sonia Severin showed a functional link between marrow adipocytes and the development of megakaryocytes (29), and Mariah Farrell revealed that bone marrow adipocytes support multiple myeloma drug resistance and induce adipocyte mimicry, increasing cell survival (30, 31).