These results contradict the results of a study involving diabetic animals (rodent models for type 2 diabetes mellitus (4 groups: sedentary + SGLT2 inhibition, sedentary + placebo, training + SGLT2 inhibition, training + placebo)) indicating that exercise training + SGLT2 inhibitor administration maximized some positive effects on variables of glycemic control (15). This evidence concerns the gene SLC5A2 and type 2 diabetes mellitus.