ENTPD1 and pancreatitis: Consistently, antifibrogenic effects of CD39 depletion have been observed in bleomycin-induced skin fibrosis (Fernández et al., 2013) and cyclosporin-induced pancreatitis (Künzli et al., 2008) models, probably through modulating the accumulation of ADO (Fernández et al., 2013) and the expression of profibrotic factors (Fernández et al., 2013)and pro-collagen proteins (Künzli et al., 2008).