LAMB2 and HIV infectious disease: Evidence demonstrates that changes in immune activity due to HIV infection may increase the pulse wave velocity (Boccara et al., 2006; Rider et al., 2014), disrupting the activity of the matrix metalloproteinase (MMPs) (Misse et al., 2001) and degrading collagen, elastin, laminin, and fibrillin within the arterial wall (Martinez-Ayala et al., 2020).