MB and chronic obstructive pulmonary disease: In a retrospective analysis by Guo et al. conducted in 187 patients, NT-proBNP level increased significantly during hospitalization only in those patients who died, without significant dynamic changes among survivors, thus predicting mortality independently from sex, age, hypertension, coronary heart disease, chronic obstructive pulmonary disease, myoglobin, creatin kinase-MB, high sensitivity troponin-I, white blood cells count, lymphocytes count, C-reactive protein, and procalcitonin (Guo et al., 2019).