TXNIP and Cushing syndrome due to macronodular adrenal hyperplasia: It was reported that the expression of TXNIP was abnormally increased in the bones of patients with Cushing syndrome (Lekva et al., 2012) and also high express in cells or in mice under the treatment of dexamethasone (Dex) (Wang et al., 2006; Reich et al., 2012).